CLOVES Syndrome Foundation, a 501(c)3 not-for-profit organization, is focused on improving the lives of CLOVES patients by funding Overgrowth and Vascular Anomaly research. Our foundation is committed to raising public awareness and providing member support by offering educational literature and resources while also establishing support networks within the medical and overgrowth communities.
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CLOVES: stands for
V Vascular Malformations
E Epidermal Nevi
S Spinal/ Skeletal Anomalies and/or Scoliosis
CLOVES is an extremely rare progressive overgrowth disorder, affecting approximately 150 people worldwide. The symptoms vary from mild soft tissue tumors to Vascular Malformations encompassing the spine or internal organs. CLOVES Syndrome is closely linked to other overgrowth disorders like M-CM (Macrocephaly-Capillary Malformation) Syndrome, Klippel-Trénaunay-Weber Syndrome, and Proteus Syndrome.